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Figure 1.

The studies inclusion and exclusion procedures.

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Table 1.

Characteristics of the association studies on maternal MTHFRC677T polymorphism and the risk of Neural tube defects (NTDs).

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Figure 2.

Forest plot of NTD risk associated with the maternal MTHFR C677T polymorphism (TT+CT vs. CC) in overall populations.

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Table 2.

Summary of comparisons for maternal MTHFRC677T polymorphism and risk of Neural tube defects (NTDs).

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Table 2 Expand

Figure 3.

Begg's Funnel plot of NTD risk associated with the maternal MTHFR C677T polymorphism (TT vs. CC +CT) in overall populations.

Each point represents a separate study for the indicated association.

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Figure 3 Expand