Figure 1.
Study design and key procedures.
Table 1.
Characteristics of the patients in this study.
Figure 2.
EGFR mutation rate in TK domain (N = 147).
Exon 20+21, mutations of exon 20 and exon 21 concurrently presented in the same patients; Exon19+21, mutations of exon 19 and exon 21 concurrently presented in the same patients.
Table 2.
Mutation characteristics of these genes.
Table 3.
Overlaps of the alterations of these driver genes.
Table 4.
Frequency of driver gene alterations in different subgroups.
Figure 3.
Rates of driver gene variations and survival analysis in patients with different histologic type and smoking status.
(a), Survival analysis of subgroups, (b) Rates of driver gene variations of subgroups. NS with AC: patients with adenocarcinoma in non-smokers, S with AC: patients with adenocarcinoma in smokers, NS with SCC: patients with squamous cell carcinoma in non-smokers, S with SCC: patients with squamous cell carcinoma in smokers.
Figure 4.
Survival analysis of driver genes.
(a), Survival analysis of all of the EGFR detected patients; (b), Survival analysis of the stage I patients. NR: not reached.