Figure 1.
Histogram of the number of CTs performed per individual.
Over 70% of participants had at least one follow-up CT. A total of 345 had 1 CT, 183 had 2 CTs and 654 had 3 or more CTs. Those that did not have follow-ups were individuals with no nodules on initial CT who chose not to return or individuals who were not yet due for follow-up by the end of the study period.
Table 1.
Demographic & Clinical Characteristics of the Screened Population at Enrollment.
Table 2.
Pulmonary Function Testing and CT Results of Screened Population.
Table 3.
Lung Cancer Cases Compared with All Screened.
Table 4.
Characteristics of Prevalent versus Incident Lung Cancers.
Figure 2.
Clinical Course of Prevalent Lung Cancer Cases Diagnosed After More Than 6 Months of Monitoring.
Graphic representation of the course of 13 lung cancer cases in 12 patients, plotted by months from enrollment. Each circle represents a point in time relative to enrollment when a CT scan was performed. Surgical resection was performed after the last point in each case. The size of the circle is proportional to the size of the nodule on CT scan. The shading indicates the density of the nodule: grey represents ground-glass density; darker shading represents mixed density and black represents more solid density. 12/13 cases were adenocarcinomas. The asterisk indicates the only patient in this group who has expired due to lung cancer (patient 1).
Table 5.
Odds Ratios for Risk Factors for the Presence of Nodules on Initial CT Scan*.
Table 6.
Lung Cancers Cases versus Participants with Benign Nodules: Comparisons at initial Visit.