Table 1.
Datasets of our collected dopamine receptor D1, D2, D3 and D4 ligands, non-ligands and putative non-ligands.
Table 2.
Datasets of our collected dopamine receptor D1, D2, D3 and D4 selective ligands against another subtype.
Table 3.
Datasets of our collected dopamine receptor multi-subtype ligands.
Table 4.
The performance of our new method 2SBR-SVM and that of previously used methods Combi-SVM, ML-kNN and RAkEL-DT in predicting dopamine receptor subtype selective ligands.
Table 5.
The performance of our new method 2SBR-SVM and that of previously used methods Combi-SVM, ML-kNN and RAkEL-DT in predicting dopamine receptor multi-subtype ligands as non-selective ligands.
Table 6.
Virtual screening performance of our new method 2SBR-SVM and that of our previously used method Combi-SVM in scanning 168,016 MDDR compounds and 657,736 ChEMBLdb compounds, and 13.56 million Pubchem compounds.
Table 7.
Top-ranked molecular descriptors for distinguishing dopamine receptor subtype D1, D2, D3 or D4 selective ligands selected by RFE feature selection method.