Figure 1.
Neurodevelopmental composite score (sensory and motor development) for the four treatment groups.
No group differences were statistically significant.
Figure 2.
Number of bouts of ultrasonic vocalizations (USV) on postnatal days 9, 11 13 & 17.
No group differences were statistically significant.
Figure 3.
Mean escape latency in the Morris water maze for the four treatment groups.
No group differences were statistically significant.
Table 1.
Summary of main effects for statistical analyses of behavioral performance across treatment groups.
Figure 4.
Number of hippocampal CA1 pyramidal neurons across treatment groups and sex.
Four treatment groups (i.e. vehicle, 0.4, 4.0 & 40 µg/kg misoprostol, s.c.) were analyzed for male mice, and two treatment groups, the vehicle and high 40 µg/kg dose group, were analyzed for females. No significant treatment effects, sex differences or sex by treatment interaction were found.