Figure 1.
Flow charts of Pep-3D-Search (a) and MimoPro (b).
Figure 2.
Solid lines indicate the process sequences of PepMapper whereas dashed lines are for that of either MimoPro or Pep-3D-Search alone.
Figure 3.
An example of text presentation of Intersection and Union of PepMapper.
Results of Intersection and Union are listed in text. The overlapped candidate peptides of 1JRH are highlighted in yellow in the two boxes.
Figure 4.
3D images of the results from Intersection and Union of PepMapper.
The candidate epitopes of 3IU3 are shown in the shape of spacefill and cpk color format with the rest amino acids in backbone. The image on the top is the result from Intersection of PepMapper whereas the bottom one is the result from Union of PepMapper. It can be clearly seen on these images that Intersection provides more confined prediction as most of the residues lie on the interface whereas Union outlines a larger area that may cover (part of) the potential epitopic region.
Table 1.
Test cases for validation and assessment.
Table 2.
Statistical results of Pep-3D-Search and MimoPro.
Table 3.
Statistical results of PepMapper.