Figure 1.
Mean Mouse Grimace Scale scores pre and post vasectomy.
MGS scores are presented on the y-axis (± 1SE) for mice receiving 2 ml/kg Saline, 20 mg/kg Meloxicam and 5 mg/kg Bupivacaine with the pre and post vasectomy recordings on the x-axis (★P = 0.002, ★★P = 0.000).
Figure 2.
Mean frequency of the composite pain scores pre and post vasectomy.
Composite pain scores are presented on the y-axis (± 1SE) for mice receiving 2 ml/kg Saline, 20 mg/kg Meloxicam and 5 mg/kg Bupivacaine with the pre and post vasectomy recordings on the x-axis (★P = 0.001, ★★P = 0.000).
Table 1.
The HomeCageScan scored behaviours that significantly decreased in frequency from pre to post vasectomy.
Table 2.
The HomeCageScan scored behaviours that were unaffected by treatment or time*treatment interaction post vasectomy.
Figure 3.
Relationship between changes in MGS and manually scored behaviour.
MGS scores of one experienced observer are presented on the x-axis and manually scored behaviours from pre to post vasectomy are presented on the y-axis; composite pain behaviour (a), wound lick (b), grooming (c) and rearing (d).
Figure 4.
Relationship between changes in MGS and automatically scored behaviour.
MGS scores of one experienced observer are presented on the x-axis and automatically scored behaviours from pre to post vasectomy are presented on the y-axis; walk left (a), walk right (b), and jump (c).
Table 3.
The correlation coefficients and P-values for the automated behaviours that were not significantly correlated with the MGS.
Table 4.
Ethogram for manual behavioural analysis (adapted from Miller et al. [5]).
Table 5.
Ethogram for automated behavioural analysis (adapted from Miller et al. [5]).