Table 1.
Clinical and demographic characteristics.
Table 2.
Cue-related activation.
Figure 1.
Cue-related activation in bilateral caudate ROIs.
Activation shown is mean activation across voxels within regions of interest. Error bars represent standard error.
Figure 2.
Regions demonstrating a significant main effect of receipt.
All regions showed greater activation for receipt of money than no money. Both ROI results (threshold of p<.01 and 19 voxels within ROI mask) and whole-brain results (threshold of p<.003 and 13 voxels) are displayed. Graphs represent mean activation magnitudes across voxels within example regions among individuals with schizophrenia (SCZ) and controls (CON). Error bars represent standard error.
Figure 3.
Regions demonstrating a Cue X Receipt interaction.
All regions showed greater activity for unexpected than for expected outcomes. Both ROI results (threshold of p<.01 and 19 voxels within ROI mask) and whole-brain results (threshold of p<.003 and 13 voxels) are displayed. Graphs represent mean activation magnitudes across voxels within example regions among individuals with schizophrenia (SCZ) and controls (CON). Error bars represent standard error.
Table 3.
Receipt-related activation.
Figure 4.
Regions demonstrating correlations between activation and anhedonia severity.
(A) Results of voxelwise correlation between Chapman physical anhedonia score and the Cue Money – No Money contrast in patients, ROI analysis (threshold of p<.01 and 19 voxels within ROI mask). (B) Results of voxelwise correlation between Chapman physical anhedonia and the Receive Money – No Money contrast in patients, whole brain analysis (threshold of p<.003 and 13 voxels.) Graphs represent mean activation across the region.
Table 4.
Correlations between Cue- and Outcome-Related Activity and Anhedonia Scores.