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Table 1.

Inclusion criteria concerning ALT and HBV DNA for all 319 patients.

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Table 2.

Baseline Characteristics of all 319 patients.

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Figure 1.

Distribution of liver necroinflammation (graded by Knodell histologic activity index) among 319 chronic hepatitis B patients.

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Figure 2.

Distribution of liver fibrosis (staged by Ishak fibrosis score) in 319 chronic hepatitis B patients.

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Figure 3.

Distribution of significant liver fibrosis (Ishak fibrosis score ≥3) among different age groups.

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Figure 4.

Comparison of Ishak fibrosis scores among HBeAg-positive patients with normal ALT (p = 0.024).

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Figure 4 Expand

Figure 5.

Comparison of Ishak fibrosis scores between ALT 1–2×ULN and ALT >2×ULN in both HBeAg-positive and HBeAg-negative patients.

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Table 3.

Clinical parameters predictive of significant liver necroinflammation and fibrosis by multivariate analysis.

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