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Table 1.

Sample summary statistics.

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Figure 1.

Significant reductions in gray matter surface area measures in WS versus TD controls.

Figure 1 shows an overlay of F-test statistics (with values indicated by the color bar) on each Freesurfer-labeled ROI that was significantly different between groups. Surface area measures in gray regions were not significantly different between WS and TD.

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Figure 2.

Significant increases in gray matter thickness measures in WS versus TD controls.

Figure 2 shows an overlay of F-test statistics (with values indicated by the color bar) on each Freesurfer-labeled ROI that was significantly different between groups. Thickness measures in gray regions were not significantly different between WS and TD.

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Figure 3.

(Top) Color coded anatomical ROI masks of subcortical regions, which showed significant group differences in volume.

(Bottom) Scatter plots of volume estimates (Z-normalized) in corresponding subcortical regions demonstrating overall decreases in volume in the areas in the WS brain versus TD controls. Presented statistical values correspond to F scores and FDR corrected q values derived from the MANCOVA. Colors in scatter plots correspond to in the color-coded anatomical ROIs in the Top portion of Figure 3.

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Table 2.

Complete list of cortical ROIs with significant group differences in surface area and/or thickness.

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Table 3.

Results from exploratory correlation analyses of brain morphological measures and Beck Anxiety Inventory scores in WS subjects.

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