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Table 1.

Demographic and behavioral characteristics of the included participants.

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Figure 1.

TBSS analysis of fractional anisotropy (FA) volumes.

Areas in red are regions where FA was significantly lower (p<0.01, corrected by TFCE) in adolescents with Internet addiction disorder (IAD) relative to normal controls without IAD. To aid visualization, regions showing reduced FA (red) are thickened using the tbss_fill script implemented in FSL. Results are shown overlaid on the MNI152-T1 template and the mean FA skeleton (green). The left side of the image corresponds to the right hemisphere of the brain.

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Table 2.

Neuroanatomical regions with reduced FA in adolescents with Internet addiction disorder relative to normal controls. (p<0.01, TFCE corrected).

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Table 3.

Group differences in diffusivity indices from volume-of-interests (corrected for age).

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Figure 2.

Correlation analysis between fractional anisotropy (FA) and behavioral measures within the Internet addiction disorder (IAD) group.

To aid visualization, regions showing significant correlations (red) are thickened using the tbss_fill script implemented in FSL. Figure 2A shows FA values in the left genu of the corpus callosum correlates negatively with the Screen for Child Anxiety Related Emotional Disorders (SCARED) (r = −0.621, p = 0.008). Figure 2B shows FA values in the left external capsule correlates negatively with the Young's Internet addiction scale (YIAS) (r = −0.566, p = 0.018).

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