Table 1.
Summary of Sex, Age and Minor Allele Frequencies by Cohort.
Figure 1.
Pooled Results of Associations between Genotypes and Measures of Anthropometry.
Adjusted for age and sex. Models used: rs35767 (IGF1)- (C/T+T/T) vs. C/C; rs7127900 (IGF2)- (C/T+T/T) vs. C/C; rs2854744 (IGFBP3- per minor (A) allele; rs2943641 (IRS1)- per minor (T) allele; rs2665802 (GH1)- per minor (T) allele; d3GHR- (fl/d3+d3/d3) vs. fl/fl. fl: full length; d3: exon-3 deletion.
Figure 2.
Pooled Results of Associations between Genotypes and Grip Strength, TGUG and Chair Rises.
Adjusted for age and sex. Timed chair rises on reciprocal of time taken in sec ×100. Models used: rs35767 (IGF1)- (C/T+T/T) vs. C/C; rs7127900 (IGF2)- (C/T+T/T) vs. C/C; rs2854744 (IGFBP3- per minor (A) allele; rs2943641 (IRS1)- per minor (T) allele; rs2665802 (GH1)- per minor (T) allele; d3GHR- (fl/d3+d3/d3) vs. fl/fl. fl: full length; d3: exon-3 deletion.
Figure 3.
Pooled Results of Associations between Genotypes and Poor Balance.
Adjusted for age and sex. Poor balance defined as inability to complete the Flamingo test for 5 s in Boyd Orr, HAS, HCS, NSHD and CaPS, and 5 s of the tandem test in ELSA. Models used: rs35767 (IGF1)- (C/T+T/T) vs. C/C; rs7127900 (IGF2)- (C/T+T/T) vs. C/C; rs2854744 (IGFBP3- per minor (A) allele; rs2943641 (IRS1)- per minor (T) allele; rs2665802 (GH1)- per minor (T) allele; d3GHR- (fl/d3+d3/d3) vs. fl/fl. fl: full length; d3: exon-3 deletion.