Figure 1.
Comparison of mixture-evoked glomerular maps to the sum of the component maps.
A, Experimentally derived responses to MV (0.25% s.v.), EB (0.25% s.v.), and their mixture displayed in pseudocolor. B, The calculated mixture response overestimates the mixture response as nearly all glomeruli remain. This can be seen when the mixture-evoked map is subtracted from the calculated map. C, Overlay of component representations expressed in different color channels to indicate glomeruli responding to one or both components (MV only: red; EB only: green; both: yellow). Glomeruli responding to both components (white arrows) are the most often overestimated by the calculated sum. D, Mean mixture-to-sum responses for all glomeruli, those that responded to both components (overlapping glomeruli), and those that only responded to one component of the mixture (non-overlapping glomeruli). Asterisks denote significant difference.
Figure 2.
Glomerular maps of binary mixtures whose components activate neighboring glomerular areas.
A, Glomerular maps of EB (0.5% s.v.), 2H (0.5% s.v.), and their mixture. B, Left: Overlay of component maps expressed in different color channels (EB only: red; 2H only: green; both: yellow). Right: Magnified image of outlined region from left showing border glomeruli. C, Mean strong component and mixture responses taken from glomeruli labeled in B. No significant difference was observed between the two responses for any of the labeled glomeruli. D, Mean suppression ratio (strong component response/mixture response) calculated from all border glomeruli for the EB+2H mixture.
Figure 3.
Little interaction in border glomeruli responses to binary mixtures.
A, Glomerular response to MV (0.1% s.v.), BA (0.5% s.v.), and their mixture. Suppressed responses were observed in two border glomeruli (white arrows) when presented with the mixture. B, Left: Overlay of component maps expressed in different color channels (MV only: green; BA only: red; both: yellow). Right: Magnified image of outlined region from left showing border glomeruli. Glomeruli G and H are glomeruli identified in A. C, Mean strong component and mixture responses from glomeruli labeled in B. A seen above, a significant difference was observed between the two responses for observed for glomeruli G and H. D, Mean SR calculated from all border glomeruli for the MV+BA mixture only, all border glomeruli, and all non-overlapping glomeruli. Asterisks denote significant difference.