Figure 1.
Flow diagram of RCTs sample selection from all reports of clinical trials with ClinicalTrials.gov registration number published by ICMJE journals from 13 September 2005 to 24 April 24 2008.
Table 1.
Randomized controlled trials (RCTs) in ClinicalTrials.gov with missing data in the registration fields of 9 WHO Minimum Data Set items at initial registration and at last change before publication date, and differences of published data to those specified in the trial registration.
Table 2.
Major changes in ClinicalTrials.gov registry fields for 8 WHO Minimum Data Set items in 31 RCTs out of 123 RCTs with one or more changes in the registry after the initial registration.*
Table 3.
Major changes of 8 WHO Minimum Data Set items* in published articles compared to the last ClinicalTrials.gov registry data before publication for 152 published RCTs in ICMJE journals.