Table 1.
Case history and clinical characteristics of autism and control donors of brain tissue samples.
Table 2.
Autism Diagnostic Interview-Revised test scores in donors of brain tissue samples.
Table 3.
Vineland Adaptive Behavioral Scales diagnostic test for autism in donors of brain tissue samples.
Figure 1.
PKA activity in different brain regions from regressive autism, non-regressive autism, and age-matched control subjects.
The autism group comprises combined regressive and non-regressive autism sub-groups. Brain homogenates were prepared, and activity of PKA was measured as described in Materials and Methods. Data represent mean ± S.E.
Figure 2.
Relative protein levels of PKA (C-α) in the frontal cortex of regressive autism, non-regressive autism, and age-matched control subjects.
Western blot analyses of C-α subunit of PKA in the frontal cortex of individuals with regressive and non-regressive autism, and age-matched control subjects are represented in Fig. 2A. The relative density of PKA (C-α) normalized with the density of β-actin (loading control) is shown in Fig. 2B. Data represent mean ± S.E.