Table 1.
Descriptive information on 11 recent HIV noninferiority trials.
Figure 1.
Difference in success rates with confidence intervals in 9 trials presenting both an ITT and a non-ITT analyses.
Table 2.
Results of 6 HIV noninferiority trials.
Table 3.
Results of 5 HIV noninferiority trials.
Table 4.
Computation of the width of 95% confidence interval according to different sample size and success rates for a fixed treatment difference of −5%.
Table 5.
Width of confidence intervals for the 11 HIV noninferiority trials according to the different statistical methods.
Table 6.
Comparison between two exact methods (CZ, Chang and Zhang and SS, Santner and Snell) applied to data from the 11 HIV noninferiority trials.