Table 1.
Sample details and treatments.
Table 2.
Tissue hydration and collagen parameters measured before (CXL-) and after (CXL+) riboflavin/UVA collagen cross-linking.
Figure 1.
Changes in collagen interfibrillar spacing following Riboflavin/UVA cross-linking.
The contour maps show collagen interfibrillar spacing (IFS) in an unswollen normal cornea (N3) and a slightly swollen keratoconus cornea (K2) before and after hypo-osmolar riboflavin/UVA cross-linking (Hypo-R CXL) and a normal unswollen cornea (N8) before and after iso-osmolar riboflavin/UVA cross-linking (Iso-R CXL). The centre of each corneal button corresponds approximately with the centre of each map.
Figure 2.
Changes in collagen fibril diameter following Riboflavin/UVA cross-linking.
The contour maps show collagen fibril diameter in an unswollen normal (N1) and keratoconus (K1) cornea before and after hypo-osmolar riboflavin/UVA collagen cross-linking (Hypo-R CXL) and an unswollen normal cornea (N7) before and after iso-osmolar riboflavin/UVA collagen cross-linking (Iso-R CXL). The centre of each corneal button corresponds approximately with the centre of each map. The locations of the stellate scar (solid line) and the scar at Descemet's membrane level (broken line) (as recorded schematically by the operating surgeon) have been superimposed onto the contour maps of K1.