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Table 1.

Demographic information of the subjects involved in the study.

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Figure 1.

Overview of our proposed method.

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Figure 2.

Illustration of hierarchical ROIs.

Left: Hierarchical ROIs in three different layers; Right: Network connections between ROIs within different layers.

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Table 2.

Number of ROIs in the hierarchy.

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Figure 3.

Explanation of the network model.

Left: Two types of nodes are included in the hierarchical network: the simple node in , and the compound node in (). Each compound node is obtained by grouping several simple nodes agglomeratively. Right: Two types of edges are included in the hierarchical network, each modeling the within-layer and between-layer interactions, respectively.

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Figure 4.

Explanation of the membership matrix.

The -th row in the membership matrix represents the composition of the node in . In our example, since is composed of the simple nodes , and in , the elements of , and in are set to , while the others in the -th row are set to .

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Figure 5.

Overview of the proposed classification scheme.

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Figure 6.

Classification comparison using different features.

The classification performance is compared between our proposed method (four-layer network features as in Method I) and the conventional volumetric method (Method IV) on 20 training/test groups. Each group contains 150 training samples and 75 test samples randomly partitioned from our data set.

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Figure 7.

Classification comparison using different hierarchical structure.

The classification performance is compared between the four-layer network features in Method I and the single layer network features in Method II on 20 training/test groups. Each group contains 150 training samples and 75 test samples randomly partitioned from our data set.

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Table 3.

Comparison of discrimination efficacy of different features.

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Figure 8.

Classification comparison using network features and volumetric features with different numbers of training samples.

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Table 4.

Configurations of classification Schemes.

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Figure 9.

Comparison of seven classification schemes on network features.

The classification accuracy is plotted over different number of training samples. For a given number of training samples, the classification accuracy is averaged over 20 training/test groups randomly partitioned from our data set using this number of training samples. The scheme configurations are shown in Table 4.

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Table 5.

Selected discriminative features.

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Figure 10.

Comparison of different metrics used for modeling the regional interactions.

The classification accuracy is plotted over different number of training samples. For a given number of training samples, the classification accuracy is averaged over 20 training/test groups randomly partitioned from our data set using this number of training samples.

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Table 6.

Comparison of different metrics for modeling the regional interactions.

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