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Table 1.

Suppose that 500 patients are treated with drug A and 500 with placebo.

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Figure 1.

Crude effect measures presented in 193 RCTs that had a dichotomous primary outcome, and adjusted effect measures presented in 53 RCTs that had a dichotomous primary outcome and adjusted for baseline variables (OR = odds ratio, RR = risk ratio, HR = hazard ratio, RD = risk difference).

* Other includes presentation of only p-values or only percentages, or no crude measure presented.

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Figure 1 Expand

Figure 2.

ORs and their accompanying RRs for the primary outcome in 16 RCTs (crude estimate) and 12 RCTs (adjusted estimate).

Dotted line represents the points where the OR and RR are the same.

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Figure 2 Expand

Figure 3.

ORs and their accompanying RRs for other outcomes or subgroup analyses in 41 RCTs.

Dotted line represents the points where the OR and RR are the same; other lines represent 20%, 50% and 100% difference between OR and RR.

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Figure 3 Expand