Figure 1.
Topology of sample biological networks.
(a) Protein structure network [7] and (b) human brain functional network extracted through functional magnetic resonance imaging [24].
Table 1.
Characteristics of considered biological networks.
Table 2.
Significance profiles of motifs in the networks.
Figure 2.
Z-score of motifs #1–#8 as a function of the percentage of removed edges for protein structure network.
The blue, green, red and cyan lines show the changes in the Z-score for random failure (failure strategy 1), systematic failure based on node degrees (failure strategy 2), systematic failure based on betweenness centralities (failure strategy 3), and systematic failure based on node closeness centralities (failure strategy 4), respectively. The case with random failure is averaged over 10 realizations.
Figure 3.
Z-score of motifs #1–#8 as a function of the percentage of removed edges for human brain functional network.
The blue, green, red and cyan lines show the changes in the Z-score for random failure, systematic failure based on node degrees, systematic failure based on betweenness centralities, and systematic failure based on node closeness centralities, respectively. The case with random failure is averaged over 10 realizations.
Figure 4.
Frequencies of motifs #1–#8 as a function of the percentage of removed edges for protein structure network.
The blue, green, red and cyan lines show the changes in the Z-score for random failure, systematic failure based on node degrees, systematic failure based on betweenness centralities, and systematic failure based on node closeness centralities, respectively. The case with random failure is averaged over 10 realizations.
Figure 5.
Frequencies of motifs #1–#8 as a function of the percentage of removed edges for human brain functional network.
The blue, green, red and cyan lines show the changes in the Z-score for random failure, systematic failure based on node degrees, systematic failure based on betweenness centralities, and systematic failure based on node closeness centralities, respectively. The case with random failure is averaged over 10 realizations.