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Figure 1.

MIPS functional analysis of the differently expression genes (data from Table S1) at 12 h (A) and 18 h (B).

The prominent part of the circle represents the down-regulated genes, and the other part represents the up-regulated genes.

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Table 1.

Gene groups that with E-value<0.05 at 12 h or 18 h.

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Table 1 Expand

Figure 2.

Accumulation of Pyruvate, Lactate and acetate at the final time of fermentation.

L, Low oxygen supply; H, high oxygen supply.

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Figure 3.

Intracellular amino acids concentration at 12 h and 18 h.

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Figure 4.

Effect of xanthine on adenosine production and concentration of xanthine over the time course of the fermentation process.

(A) Effect of xanthine on adenosine production. The blue symbol denotes sufficient xanthine supply in the fermentation process. The red symbol denotes no xanthine addition in the fermentation process (B) Xanthine concentration over time course of the fermentation process under different DO levels.

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Figure 5.

Accumulation of Adenine, AMP and IMP at the final time point of the fermentation process.

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Figure 6.

The putative signal network in response to low oxygen supply.

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Figure 7.

Effect of different addition on adenosine productivity.

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