Figure 1.
Flow chart of the NUGENOB trial and genotyping success of MC3R variants.
Legend to Figure 1: weight loss is expressed as mean ± standard deviation.
Figure 2.
MC3R polymorphisms genotyped in this study and linkage disequilibrium (r2) measures.
Table 1.
Basic statistical analysis of MC3R variants.
Table 2.
Drop out according to MC3R genotypes and type of diet.
Figure 3.
Crude weight loss in the NUGENOB trial by rs6014646, rs3746619 (Thr6Lys), rs3827103 (Val81Ile) and rs1543873 MC3R genotypes.
Legend to Figure 3: P-values were calculated from multivariate models (see text).
Table 3.
MC3R variants, weight loss and waist circumference change in the NUGENOB trial.
Table 4.
MC3R variants, fat mass and resting energy expenditure (REE) change in the NUGENOB trial.