Figure 1.
Chemical structure of MTP.
Figure 2.
Interstitial fibrosis in hypertrophic hearts.
A. normal control heart and B. hypertrophic heart with Masson's Trichrome stain. Blue = fibrous collagen, red = myocytes, black = nuclei, C: Picrosirius Red stain on hypertrophic heart, red = fibrous collagen, pale yellow = myocytes, black = nuclei. D: CNA35-Cy3 (red) and MTP-FITC (green) double stain on hypertrophic heart.
Figure 3.
Perivascular fibrosis staining.
A: Masson's Trichrome staining. B: CNA35 mono staining for collagen fibers. C: MTP mono staining for myocyte. D: Double staining for collagen (CNA35-Cy3, red) and myocyte (MTP-FITC, green).
Figure 4.
Staining of neointima in coronary arteries in Ab+I/R+DeAb heart in rats.
A: Picrosirius Red staining. B: Masson's Trichrome. C: CNA35 mono staining. D: Double staining for collagen (CNA35-Cy3, red) and myocyte (MTP-FITC, green).
Figure 5.
Staining of fibrosis in infarcted area.
A and B: Masson's Trichrome, C: Picrosirius Red staining. D: Double staining for collagen (CNA35-Cy3, red) and myocyte (MTP-FITC, green).
Figure 6.
Images of isolated myocytes and fibers.
A: Bright-field image of myocytes without staining. B: Bright-field image of myocytes with H-E staining. C: Double staining for collagen (CNA35-Cy3, red) and myocyte (MTP-FITC, green). Florescent probe could distinguish fibers from alive and dying (round) myocytes. D: Enlarged myocytes labeled with MTP-FITC. Blue is DAPI for nuclei.