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Figure 1.

Co-registered T1-weighted TFE, TOF, T2-weighted TSE, pre- and post-contrast T1-weighted TSE images of a transverse section of a plaque in the internal carotid artery.

The right bottom panel displays the plaque components: red = lumen; green = outer vessel wall; yellow = LRNC; orange = calcifications; remaining vessel wall area = fibrous tissue. IPH was scored as being present (asterisk in T1-weighted TFE and TOF images) and the FC was designated as thin and/or ruptured (arrow in post-contrast T1-weighted TSE image).

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Figure 1 Expand

Figure 2.

Transverse T2-weighted TSE and fluid-attenuated inversion recovery images showing WMLs, mainly located adjacent to the ventricles (arrows).

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Figure 2 Expand

Table 1.

Patient characteristics (n = 50).

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Table 1 Expand

Table 2.

Results of Spearman rank correlation analyses for associations between clinical parameters, ipsilateral WML volume at baseline and ipsilateral WML volume progression after one year. Significant results are displayed in bold.

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Table 2 Expand

Figure 3.

Scatter plots showing the relation between total plaque volume and ipsilateral WML volume at baseline (A) and ipsilateral WML volume difference after one year (B); and between LRNC volume and ipsilateral WML volume at baseline (C) and ipsilateral WML volume difference after one year (D).

Box-and-Whisker plots showing the relation between fibrous cap status and WML volume at baseline (E) and WML volume difference after one year (F). Box-and-Whisker plots showing the relation between intraplaque hemorrhage and WML volume at baseline (G) and WML volume difference after one year (H).

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