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Figure 1.

Lifetime from the linear noise Fokker–Planck approximation at low confinement.

Lifetime (correlation time) as a function of burst for (a) small and (b) large bursts, normalised to the no-burst, unit-stoichiometry case for monomers , dimers and trimers . The region above ca. defines the high- region, where lifetimes become insentitive to . Note that the lifetime of monomer decreases whereas that of the dimer and trimer increases.

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Figure 1 Expand

Figure 2.

(Colour) Decay-rate function from the linear noise Fokker–Planck approximation at low confinement.

Decay-rate function for several burst values . (a) Monomers . (b) Dimers . (c) Trimers . For dimers and trimers there is a threshold burst above which the becomes non-monotonic in . Furthermore, it develops a maximum and it appears at later times with increase in burst .

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Figure 2 Expand

Figure 3.

Lifetime from the full-master-equation trajectories.

Lifetimes as a function of system volume for constant burst , each normalised to its corresponding system. (a) No burst, . (b) Higher burst, for monomers , dimers and trimers . Note that the system becomes insensitive to at large enough , as the linear-noise approximation predicts (see “Low confinement: the linear-noise approximation” in “Results”). As volume decreases, the system departs from linear-noise behaviour. Note that trimers are insensitive to volume as they are not a reactant in a non-linear reaction.

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Figure 3 Expand

Figure 4.

(Colour) Lifetime from the full-master-equation trajectories.

Lifetimes normalised to their value at . (a) Monomers , (b) dimers , (c) trimers . N.B.: The void region for small corresponds to population fluctuations becoming larger than the mean. Shown is an interpolation of data sampled at intervals .

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Figure 4 Expand

Figure 5.

(Colour) Decay-rate function from the full-master-equation trajectories.

Decay-rate function for (a) monomers , (b) dimers , and (c) trimers as volume shrinks at . is defined as the position of the maximum. Shrinking volume alone reduces , as opposed to increasing , see Fig. 1. Similar trend is also shown by the trimers.

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Figure 5 Expand

Figure 6.

(Colour) ACF initial curvature from the full-master-equation trajectories.

ACF initial curvature, , normalised by its absolute value at . (a) Monomers , (b) dimers , (c) trimers . This quantity serves as a lower dimensional read-out of the decay-rate function . N.B.: The void region for small corresponds to population fluctuations becoming larger than the mean. Shown is an interpolation of data sampled at intervals .

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Figure 6 Expand

Table 1.

ACF characteristics upon increasing burst and confinement .

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Table 1 Expand