Table 1.
Characteristics of 164 patients and indications for RHC.
Figure 1.
DE mPAP (B) was better correlated with RHC than sPAP (A). Dotted lines mark virtual best correlation of 1 and solid lines mark the real correlation. r indicates the correlation coefficient, sPAP indicates systolic pulmonary artery pressure.
Figure 2.
Bland-Altman plot of DE estimates of PA and RHC pressures for sPAP (A) and mPAP (B).
Smaller bias and limits of agreement present in mPAP measurements compared to sPAP measurements.
Figure 3.
Analysis of relative differences and ROC analysis of mPAP for diagnosis of PH.
A, the relative positive and negative deviation between DE and RHC were larger for sPAP than mPAP. B, ROC analysis reveal an excellent diagnostic accuracy of mPAP for the diagnosis of PH with an area under the curve (AUC) of 0.95.
Table 2.
Diagnostic value of different mPAP cut-offs for diagnosis of PH.
Figure 4.
Study flowchart in accordance to the STARD criteria.
In phase 0 diagnostic criteria were evaluated in 164 patients undergoing DE and RHC. In phase 1 the calculated cut-off value for mPAP was validated in a cohort of patients with the suspicion of PH.
Table 3.
Demographics, RHC and DE measurements of the validation group (n = 50).