Figure 1.
Structure of the saxitoxin analogs identified in Lyngbya wollei (adapted from [7]).
Figure 2.
Organization of the PST biosynthesis cluster in Lyngbya wollei, scale indicates gene size in base pairs, direction of arrowed boxes indicates direction of transcription.
Table 1.
The saxitoxin biosynthesis genes in Lyngbya wollei and their homology-based functions identified using BlastX (percentage identity is reported).
Figure 3.
Amino acid alignment of the dioxygenases encoded by the various saxitoxin clusters.
The conserved regions that are modified in sxtdiox are boxed.
Figure 4.
Proposed biosynthetic pathway for the PSTs produced by Lyngbya wollei.
The gray shaded area highlights the steps that are unique to L. wollei.