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Figure 1.

Global distribution of long runs of homozygosity.

The average total length of the genome in runs of homozygosity in a number of length categories is plotted for each continental region. The data for runs under 1 Mb (inset) are plotted on a different scale. For comparison, chromosome 1 is 224 Mb in length.

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Figure 1 Expand

Figure 2.

Runs of homozygosity in African hunter-gatherers and agriculturalist heritage populations.

The average total length of the genome in ROH in a number of length categories is plotted.

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Figure 2 Expand

Table 1.

Continental mean genomic inbreeding coefficients (FROH).

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Table 1 Expand

Figure 3.

Individual patterns of long runs of homozygosity.

The number of runs of homozygosity compared to the total length in ROH for individuals from a number of illustrative populations. The Karitiana are from the Brazilian Amazon, the Mandenka from Senegal and the Baluchi from Pakistan. Cryptically inbred French, Japanese and Mandenka individuals plot to the right of the main population cluster in each case, as they carry longer ROH, but not that many more ROH. The length in ROH is very variable in the consanguineous Baluchi and Karitiana populations.

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Figure 3 Expand