Figure 1.
Schematic representation of uridine synthesis and its transport into the cell.
MP = monophosphate.
Table 1.
Demographics, HIV-1 infection and antiretroviral exposure parameters.
Table 2.
Anthropometric, metabolic data and plasma uridine levels.
Table 3.
Correlations of serum uridine levels with metabolic, infectious and treatment factors.
Figure 2.
Expression of genes encoding enzymes involved in uridine metabolism and concentrative nucleoside transporters (CNT).
Data from subcutaneous adipose tissue of uninfected controls and HIV-1 infected patients. Figure shows means + SEM for each specific mRNA concentration (expressed as ratio relative to HPRT mRNA) from 6-8 patients/group. P values for statistical comparisons between groups are shown when <0.05. MP = monophosphate. HALS- = No HIV-1/HAART-associated lipodystrophy syndrome. HALS+ = HIV-1/HAART-associated lipodystrophy syndrome. HAART = Highly Active AntiRetroviral Therapy.