Figure 1.
Metabolic pathways of n-6 and and n-3 fatty acids.
Dashed arrows indicate pathways absent in human mammals. Figure is based on modified figures form Duchen et al. Glaser et al., and Park et al. [11], [12], [40]. LA = linoleic acid, GLA = gamma linolenic acid, DGLA = Dihomo-gamma-linolenic acid, AA = arachidonoc acid, A = adrenic acid, ALA = alpha-limolenic acid, EPA, = eicospentaenoic acid, DPA = docosapentaenoic acid, DHA = docosahexaenoic acid; LTs = leukotrienes, PGs = prostaglandins, TXs = thromboxanes, RVs = Resolvins.
Table 1.
Characteristics of study population.
Figure 2.
Pairwise linkage disequilibrium measured by Lewontin's D' and r2 for the common five single nucleotide polymorphisms (SNP) in the KOALA (Panel A) and the LISA (Panel B) birth cohort studies.
Table 2.
Associations of the five analyzed variants in the FADS1 FADS 2 gene region with fatty acids.
Table 3.
Association of FADS1 FADS 2 variants with parental reported eczema.
Table 4.
Association of fatty acids with parental reported eczema.