Figure 1.
Enterococcus faecalis OG1SSp (pINY1801, AS+) infectious endocarditis aortic valve and aortic vegetations.
Vegetations are circled.
Table 1.
Enterococcal aggregation substance enhances vegetation production in endocarditis in rabbits.
Table 2.
Active immunization against AS+ E. faecalis worsens infectious endocarditis after challenge with AS+ enterococci.
Table 3.
IgG Fabs against aggregation substance reduce the severity of enterococcal endocarditis after challenge with AS+ E. faecalis.
Figure 2.
IgG antibodies to enterococcal aggregation substance enhance aggregation of E. faecalis in vitro, whereas Fabs prevent aggregation.