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Figure 1.

Survey of ADAMTS13 inhibitor and anti-ADAMTS13 antibodies on diagnosis in patients with a severe (<5%) or a mild (13–18%) ADAMTS13 deficiency.

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Figure 2.

ADAMTS13 value on diagnosis.

Dark grey squares: deficient ADAMTS13 activity with inhibitory or non-inhibitory anti-ADAMTS13 antibodies; light grey squares: deficient ADAMTS13 activity with suspected inhibitory or non-inhibitory anti-ADAMTS13 antibodies; white squares: detectable (≥20%) ADAMTS13 activity. Grey area delimits ADAMTS13 values of normal subjects. Abbreviation: TMA, thrombotic microangiopathy.

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Table 1.

Clinical Characteristics of 214 Patients with Thrombotic Microangiopathy According to ADAMTS13 Activity.

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Table 2.

Results of Laboratory Testing in 214 Patients with Thrombotic Microangiopathy According to ADAMTS13 Activity.

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Table 3.

Treatment and Outcome in 214 Patients with Thrombotic Microangiopathy According to ADAMTS13 Activity.

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Table 4.

Association Between Patient Characteristics and ADAMTS13 Deficiency Using Multivariate Analysis.

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Table 5.

Internal Validation to Predict Severe ADAMTS13 Deficiency at Clinical Presentation.

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