Figure 1.
Patient recruitment and assignment of patients to ‘confirmed’, ‘probable’, or ‘TB unlikely’ groups.
Table 1.
Demographic characteristics of patients.
Table 2.
Clinical features of 96 pediatric TB suspects.
Table 3.
Sensitivity of MODS, smear and MGIT against clinical gold standard.
Figure 2.
MODS positive in relation to Smear and MGIT, by patient.
* This patient was deemed a false positive due to H37Rv (the positive control strain) identification by spoligotyping.
Figure 3.
Detection rates of Smear, MGIT and MODS in relation to TB treatment.
P values for comparison of detection rates between MODS and MGIT. * TAT: Turn around time.
Figure 4.
Time-dependent sensitivity of smear, MODS and MGIT.
In the 73 samples which were both MGIT and MODS positive, the time dependent sensitivities of MODS were higher than MGIT on both day 7 (P<0.001) and day 14 (P = 0.04).
Figure 5.
Time to MGIT positive and MODS positive in relation to smear grade.
Filled dots are samples positive by either MGIT or MODS, lines are scatter plot smoothers. Both MGIT and MODS had a negative Spearman rank correlation with smear grade (P<0.001).
Figure 6.
Position of contamination observed in MODS Plates.
C. Positive control (H37Rv), S. Sample, F. Contaminated with fungi, Rv. Contaminated with H37Rv, Rv(4). Four experiments contaminated with H37Rv at this position.