Table 1.
Means and standard deviations (±SD) of demographic variables for the alcohol-dependent (n = 24) and healthy (n = 24) subjects, and biological variables for alcohol-dependent subjects.
Figure 1.
Between groups comparison of ADC images.
p<0.001 FDR corrected.
Table 2.
Regions of significant increases in ADC in alcoholics compared to healthy subjects.
Figure 2.
Between groups and regression analyses in the left parahippocampus gyrus.
A/Regions where negative correlation between free recall scores and the ADC was detected in alcoholics are rendered on a template image. The colored bar represents the T-score of significant voxels. B/Mean ADC in the left para-hippocampus gyrus (MNI coordinates: x = −16,y = −26,z = −8) of alcoholic and healthy control subjects. C/Plotted values of verbal memory Z-scores and mean ADC cluster values, in alcoholdependent group at the highest peak-voxel (left para-hippocampus gyrus) detected by the regression analysis (MNI coordinates: x = −16,y = −26,z = −8; R2 = 0.184; p = 0.046).
Table 3.
Regions of significant volume decreases in alcoholics compared to healthy subjects.