Table 1.
Patient characteristics according to blood-group.
Figure 1.
Relation between FVIII half-life and pre-infusion VWF-antigen levels.
Panels show the correlation between FVIII half-life and VWF pre-infusion levels in severe haemophiliacs with blood-group non-O (panel A) and blood-group O (panel B). Drawn lines represent best-fit obtained after univariate linear regression.
Table 2.
Results of univariate linear regression analysis blood-group non-O patients.
Table 3.
Results of univariate linear regression analysis blood-group O patients.
Figure 2.
Calculated FVIII half-life versus observed FVIII half-life.
Calculated FVIII half-lives were obtained using equations 1 or 2 (Panels A and B, respectively), using pre-infusion VWF and propeptide levels, and are plotted versus observed FVIII half-lives of blood-group non-O (panel A) and blood-group O patients (panel B). Solid lines represent ideal correlation between calculated and observed half-lives, while dotted lines indicate 20% deviation margins.
Table 4.
Results of multivariate linear regression analysis blood-group non-O patients.
Table 5.
Results of multivariate linear regression analysis blood-group O patients.