Figure 1.
Circular representation of the B. hyodysenteriae WA1 genome, with annotated genes.
A, Chromosome (CI); B , Plasmid (PI). Circles range from 1 (outer circle) to 6 (inner circle) for CI and I (outer circle) to IV (inner circle) for PI. Circles 1/I and 2/II, genes and forward and reverse strand; circle 3, tRNA genes; circle 4, rRNA genes, circle 5/III, GC bias/skew ((G-C)/(G+C); red indicates values >0; green indicates values <0); circles 6/IV, A+T percentage content. All genes are color-coded according to Cluster of Orthologous Group (COG) functions: violet for translation, ribosomal structure and biogenesis; plum for RNA processing and modification; pink for transcription; deep pink for DNA replication, recombination and repair; hot pink for chromatin structure and dynamics; wheat for cell division and chromosome partitioning; light salmon for nuclear structure; yellow for defence mechanisms; gold for signal transduction mechanisms; pale green for cell envelope biogenesis, outer membrane; spring green for cell motility and secretion; lawn green for cytoskeleton; yellow green for extracellular structures; aquamarine for intracellular trafficking, secretion, and vesicular transport; medium aquamarine for posttranslational modification, protein turnover, chaperones; cyan for energy production and conversion; deep sky blue for carbohydrate transport and metabolism; sky blue for amino acid transport and metabolism; light slate blue for nucleotide transport and metabolism; orchid for coenzyme metabolism; medium orchid for lipid metabolism; dark orchid for inorganic ion transport and metabolism; blue violet for secondary metabolites biosynthesis, transport and catabolism; slate grey for general function prediction only; grey for function unknown; gray for not in COGS; black for tRNA.
Table 1.
General genomic features predicted for B. hyodysenteriae WA1.
Table 2.
Distribution of Cluster of Orthologous Genes categories in B. hyodysenteriae WA1 and other spirochetes.
Table 3.
Similarities of predicted B. hyodysenteriae proteins to those from 716 complete microbial genomes*.
Table 4.
COG analysis of Clostridium-like and Escherichia-like genes identified in B. hyodysenteriae WA1.
Figure 2.
Central metabolic pathway construction for B. hyodysenteriae WA1.
Table 5.
Genes with potential roles in pathogenesis and virulence in B. hyodysenteriae.