Figure 1.
CONSORT Diagram showing the disposition of subjects randomized to receive creatine monohydrate or an equivalent number of placebo capsules for 14 weeks.
Table 1.
Baseline Characteristics of the Study Population.
Figure 2.
Muscle strength before and after 14 weeks of study.
Large rectangles represent the average values, while smaller rectangles individual data before and after creatine supplementation. Similarly, large circles represent the average values, while smaller circles individual data before and after placebo supplementation. Data are the sum of strength (1 RM) in 8 muscle groups in subjects randomized to receive creatine monohydrate or placebo. Strength increased significantly within each treatment group (P<0.01), but there was no significant difference between groups in the magnitude of the increase (average increase 44 and 42% (difference 2%, 95% CI −9.5% to 13.9%) in creatine and placebo, respectively, P = 0.58).
Table 2.
Muscle Strength and Energetics at Baseline and Changes on Study.
Table 3.
Body Composition at Baseline and Changes on Study.
Table 4.
Safety and Biochemical Measurements at Baseline and Changes on Study.