Table 1.
Characteristics of the study population
Table 2.
Plasma profile comparison between ARDS and controls
Figure 1.
Box plot of plasma profiles of PI3, SLPI, HNE, and HNE/PI3 among pre-ARDS, the ARDS and the controls.
Pre-ARDS: plasma sample (n = 19) collected during 7-day period before ARDS diagnosis; ARDS: samples (n = 67) collected within 48-hour of ARDS diagnosis; Control: samples (n = 63) collected within 48-hour of ICU admission; Ref: anonymous plasma samples from healthy individual (n = 28). The plasma profiles among three groups were tested by general linear model with adjustment of age, gender, pulmonary injury, pre-admission steroid use, and higher APACHE III score on ICU admission (P values showed in the plots).
Table 3.
ANOVA analyses of plasma profiles among the pre-ARDS, ARDS and the Controla
Figure 2.
Box plot of plasma profile changes in clinical progress of ARDS.
Pre-ARDS: plasma sample (n = 19) collected during 7-day period before ARDS diagnosis; ARDS: samples (n = 67) collected within 48-hour of ARDS diagnosis; Post-ARDS: samples (n = 105) collected between Day 2 and Day 4 of ARDS diagnosis. The trends of plasma profiles across ARDS development, as measured by reciprocal of days between sampling dates relative to ARDS diagnosis, were tested by mixed effect models, adjusted for age, gender, type of pulmonary injury, pre-admission steroid use, and APACHE III score on ICU admission (P values showed in the plots).
Table 4.
Changes of plasma profiles between paired samples