Table 1.
Sequencing and mapping statistics.
Figure 1.
Distribution of depth-coverage.
The distribution of depth-coverage of the entire genome is shown for both SOLiD and GA. Poisson and gamma distributions with comparable average mean values are imposed on the observed distribution. Only reads that are mapped with no more three mismatches and without inconsistent mate-pairs are counted in the depth-coverage calculation.
Table 2.
Depth-coverage statistics.
Table 3.
Variants.
Table 4.
Experimentally validated single nucleotide variants.
Table 5.
Indels.
Figure 2.
The relationship between average depth-coverage and variant detection sensitivity.
The x-axis is the average depth-coverage. The y-axis is the theoretical fraction of genome where potential variants can be detected under the assumptions described above. The red dot marks 95% sensitivity at 13× coverage.
Table 6.
Comparing platforms.