Figure 1.
Flow chart of study participants.
Included study participants from August 2005 until February 2007. PV = post vaccination. RT−PCR = Reverse transcriptase polymerase chain reaction. Wks = weeks and yr = year.
Table 1.
Comparability of intradermally and subcutaneously vaccinated groups
Figure 2.
Protective virus neutralization after intradermal or subcutaneous vaccination against yellow fever.
Comparison of reciprocal serum dilutions at which 80% of yellow fever virus is neutralized in constant virus – varying serum dilution test after intradermal and subcutaneous YF vaccination in primary vaccinated participants (n = 155). Bars represent 95% Confidence Intervals (CI). Virus neutralizing capacity of serum in both groups was performed at similar time points but indicators are juxtaposed for visual enhancement. VN = virus neutralization.
Figure 3.
Pre- and post vaccination virus neutralizing capacity of serum of previously vaccinated participants.
Pre- and postvaccination (2 weeks) serum dilutions at which 80% VN occurred in previously vaccinated participants. When 80% VN was not reached by the least diluted serum (1∶16), samples were defined as <16 (reciprocal serum dilution). VN = Virus neutralization.
Figure 4.
Virus neutralizing capacity of YF-RNA negative and positive sera.
Comparison of reciprocal serum dilutions, of serum obtained 4 weeks after vaccination, at which 80% VN occurred between positive and negative YF-17D RNA detection by RT-PCR in primary vaccinated participants (N = 24). Bars represent the median reciprocal serum dilution. VN = Virus neutralization.
Table 2.
Solicited adverse events after primary and booster YF-17D vaccination.