Table 1.
Clinical characteristics of stroke patients and controls.
Table 2.
PCSK9 Genotype frequencies (%) for cases and controls.
Figure 1.
Effect of PCSK9 variants on the mean atherosclerosis score of the circle of Willis cerebral arteries.
In the autopsy study, each of the nine branches of the circle of Willis was scored semi-quantitatively (0 = normal, 1 = slight: streaks with or without elevated fibrous lesions, 2 = moderate: fibrous lesions that cause<50% stenosis, 3 = severe:>50 stenosis with extensive atherosclerosis (fatty, fibrous, calcified lesions)) giving a range of scores from 0 to 27. Results are mean±SEM.