Figure 1.
2D representation of the human (red) and mouse (blue) odorant spaces.
Map regions with an over-representation of binding sites from either human or mouse are circled (a–d). An example of a pair of human-mouse orthologs (MOR27-1 and OR52P1) with identical binding site is indicated in (e).
Figure 2.
A. 3D representation of the human (red) and mouse (blue) odorant spaces.
Shown in dark green is a mouse-specific cluster (consisting of MOR232-2, MOR232-5, MOR233-1, MOR233-7, MOR235-1). B. A phylogenetic tree based on the full protein sequence that includes all five genes (dark green) in the mouse specific cluster shown in A. The five genes do not form a monophyletic clade, but instead are interspersed among human (red) and other mouse (blue) genes.
Figure 3.
2D representation of the human (red) and mouse (blue) odorant spaces.
The ‘Iva mouse OR genes’ (yellow) do not form a single cluster (A). High resolution 2D representations of map regions I (B) and II (C) reveal that human OR binding sites are interspersed with the mouse Iva ORs in both regions.