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Development of AI-based dopamine transporter (DAT) image generation technique using early phase [18F]-FP-CIT PET imaging

Fig 2

Two representative cases with transaxial and MIP images from paired early-phase, generated delayed-phase, and real delayed-phase PET scans in the internal validation set.

(a–f): Case 1: 73-year-old male with essential tremors showing no significant reduction in uptake in the bilateral striatum. (g–l): Case 2: 40-year-old male with PD showing decreased DAT binding in the striatum, especially the PP. In each case, the transaxial and MIP images are arranged from left to right in the following order: early-phase PET (a, d, g, j), generated delayed-phase PET (b, e, h, k), and real delayed-phase PET (c, f, i, l). Abbreviations: MIP, maximum intensity projection; PET, positron emission tomography; PD, Parkinson’s disease; DAT, dopamine transporter; PP, posterior putamen.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0349375.g002