Estrogen deficiency induces pelvic floor muscle atrophy via ERα/GLUT4 pathway
Fig 6
In vivo experiments to validate the effect of ERα/GLUT4 axis on PFM.
(A, B) H&E staining results of the PFM of rats in different groups. (C-E) Fast (red) and slow (green) muscle staining results of the PFM of rats in different groups. (F, G) Immunohistochemical staining of GLUT4 in the PFM of rats in different groups. (H, I) Western blotting results of GLUT4, PGC1α and TFAM in the PFM of rats in different groups. Data are presented as mean ± SD. *p < 0.05, **p < 0.01.