Serum cholinesterase as a biomarker for sepsis-associated immunosuppression via Hub gene RORA
Fig 12
Validation of CHE Concentration and RORA mRNA Expression in CLP Mice.
(A–C) Violin plots showing concentrations of serum IL-6 (A), IL-1β (B), and TNF-α (C) in CLP and Sham groups; (D) Violin plot of serum cholinesterase (CHE) activity in CLP and Sham groups; (E) Bar graph depicting relative mRNA expression of RORA in the spleen of Sham and CLP groups; (F) Correlation plot showing the relationship between RORA mRNA expression and CHE Concentration. (G-I) Correlation plot showing the relationship between CD4 ⁺ T, CD8 ⁺ T, CD3 ⁺ T cell counts and CHE concentration. Statistical significance: *P < 0.05, **P < 0.01, ***P < 0.001.