Serum cholinesterase as a biomarker for sepsis-associated immunosuppression via Hub gene RORA
Fig 5
Identification of hub differentially expressed genes (DEGs) and analysis of functional enrichment.
(A, B) LASSO algorithm-based variable selection showing coefficient plots and partial likelihood deviance. (C) The Venn diagram showing overlapping genes leading to the identification of the hub gene RORA. (D, E) Volcano plot and heat maps of the DEGs between the high and low RORA expression groups. (F) The top 20 genes associated with RORA are shown. (G, H) GO and KEGG pathway analyses of the DEGs between the high and low RORA expression groups. (I, J) GSEA of the DEGs between the high and low RORA expression groups.