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Calcitriol attenuates diethylnitrosamine-induced hepatic fibrosis in rats by reducing oxidative stress and fibrogenic mediators

Fig 6

Effects of calcitriol on hepatic SOD-1, and GPX-1 gene expression in DEN-induced liver fibrosis.

The levels of hepatic SOD-1 (A), and GPX-1 (B) gene expression in all experimental groups. DEN significantly decreased SOD-1 and GPX-1 expression compared with CON. Calcitriol partially enhanced SOD-1 and GPX-1 levels. Data are presented as mean ± SD, n = 6/group. *p < 0.05 when compared with the CON group, #p < 0.05 when compared with the DEN group.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0347908.g006