Unraveling the role of ChREBP in lung adenocarcinoma: Expression, regulatory networks, and potential functional impact
Fig 4
Enrichment analysis of DEGs associated with dnChREBP overexpression in NCI-H1975 cells.
(A) Gene ontology (GO) analysis displaying the enriched biological processes related to DEGs, indicating fold enrichment and significance levels (−log10 adjusted p-value). (B) Hallmark gene sets highlighting significant pathways associated with the expression changes. The gene ratio and adjusted p-values are shown. (C) Interaction network of hub genes, illustrating their interconnections and potential regulatory relationships. (D) Venn diagram illustrating the overlap of genes associated with the EMT Hallmark, the extracellular space GO term, and the identified hub genes.