Unraveling the role of ChREBP in lung adenocarcinoma: Expression, regulatory networks, and potential functional impact
Fig 3
Transcriptome analysis of NCI-H1975 LUAD cells overexpressing dnChREBP.
(A) Brief diagram outlining the key steps of RNA sequencing analysis. (B) Heatmap displaying sample-to-sample distances calculated from the variance-stabilizing transformation of count data for overall gene expression. (C) Volcano plot illustrating differentially expressed genes (DEGs); red dots represent upregulated genes, blue dots indicate downregulated genes, and grey dots denote unchanged genes (adjusted p-value < 0.05). (D) Chromosomal localization of DEGs. The DEGs are plotted at their chromosomal positions.