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Fecal microbiota transplantation mitigates respiratory infection in rats exposed to hypobaric hypoxia by modulating the NLRP3 inflammasome and mucosal immunity

Fig 5

FMT increased sIgA levels in streptococcus pneumoniae-infected rats after hypobaric hypoxia challenge.

sIgA: secretory immunoglobulin A; NN: normobaric normoxia; HH: hypobaric hypoxia; NN + SPI: normobaric normoxia + streptococcus pneumoniae infection; HH + SPI: hypobaric hypoxia + streptococcus pneumoniae infection; HH + FMT: hypobaric hypoxia + fecal microbiota transplantation; HH + FMT + SPI: hypobaric hypoxia +fecal microbiota transplantation + streptococcus pneumoniae infection.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0347857.g005